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NMH | 2024 72 Neonatal Encephalopathy Case No. EGA BW (g) Delivery Method Delivery Method Indication Apgars 1, 5, 10, 15, 20 PPV at 10 mins Min pH within 60 min Max BE within 60 min Seizures Y/N TH Grade of NE Summary of MRI brain Organ Involvement Outcome Placental Histology Classification 1 36+6 3000 Emer- gency C-Section (GA) Fetal bra- dycardia, placental abruption 1, 3, 3 Yes 6.8 unre- cord- able Yes Yes 3 None Ventilated, multi-organ dysfunction Died on day 3 of life, coro- ner's post- mortem not directed Features of placetal abruption, low grade fetal vascular malp- erfusion 1, 2, 3, 4, HIE inborn 2 38+3 3225 Sponta- neous vaginal (water- birth) Sponta- neous labour 1, 2, 4 Yes 7.07 -13 Yes Yes 2 Abnormal: bilateral periven- tricular pattern of ischaemia/ infarction Ventilated, hepatic and renal dysfunction Discharged home on day 23 of life Acute chorioamnion- itis, maternal vascu- lar malperfusion HIE 1, 2 3 39+0 2475 Emer- gency C-Section Antepartum haemor- rhage, Fetal bradycardia 0, 2, 2 Yes 6.83 -16 Yes Yes 3 Abnormal: unilateral thalamic pattern of ischaemia/ infarction Ventilated, multi-organ dysfunction Died on day 3 of life, coro- ner's post mortem not directed Torn velamentous cord, maternal and low grade fetal vas- cular malperfusion 1, 2, 3, 4 HIE inborn 4 39+0 2845 Emer- gency C-Section (GA) Abnormal CTG, meco- nium stained liquor 1, 2, 5 Yes 6.83 -18 Yes Yes 3 Abnormal: global pattern of ischaemia/ infarction Ventilated, multi-organ dysfunction Died on on day of life 8, cor- oner's post mortem not directed High grade FVM. 1, 2, 3, 4, HIE inborn 5 39+5 3075 Operative vaginal (ventouse) Fetal bra- dycardia, shoulder dystocia 2, 7, 8 No 6.91 -17 No Yes 2 Normal No Discharged on day 7 of life Decidual necrosis 3, 4 HIE inborn 6 40+1 3500 Operative vaginal (ventouse) Abnormal CTG, Shoul- der dystocia 3, 4, 5 Yes 7.2 -8.1 No Yes 2 Abnormal: bilateral thalamic pattern of ischaemia/ infarction Ventilated Discharged home on day 5 of life Increased NRBC and meconium. 1, 2 HIE inborn 7 41+4 3510 Operative vaginal (ventouse) Abnor- mal CTG, meconium, maternal pyrexia 3, 4, 7 No 6.97 -16.7 Yes Yes 2 Normal Ventilated, meconium aspiration syndrome Discharged home on day 8 of life Acute chorioamnion- itis, low grade villitis. 3, 4, HIE inborn Hypoxic Ischaemic Encephalopathy: Inborn (7)