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NMH | 2024 74 Neonatal Encephalopathy Classification: 1) Apgar score ≤5 at 10 mins of age 2) Continued need for resus at 10 mins after birth 3) pH <7.0 within 60 mins of birth 4) Base excess ≥ 16.0 within 60 mins of birth Case No. EGA BW (g) Delivery Method Delivery Method Indication Apgars 1, 5, 10, 15, 20 PPV at 10 mins Min pH within 60 min Max BE within 60 min Seizures Y/N TH Grade of NE Summary of MRI brain Organ Involvement Outcome Placental Histology Classification 5 39+1 3560 Sponta- neous vaginal IOL poor obstet- ric history/ mater- nal discomfort 7, 4, 4 Yes 6.99 -15.5 No Yes 2 Normal No Transferred to referring hospital on day 6 of life MIR and FIR. 1, 2, 3, HIE outborn 6 39+3 3010 Operative vaginal (ventouse) Fetal bradycardia 3, 4, 6 No 6.89 -13.8 No Yes 2 Normal Ventilated Discharged home on day 7 of life No placenta in NMH 3 HIE outborn 7 39+6 2870 Sponta- neous vaginal Breech (undiag- nosed) 1, 4, 6 Yes 6.69 -24.2 No Yes 3 Normal Ventilated Transferred to referring hospital on day 4 of life No placenta in NMH 2, 3, 4, HIE outborn 8 39+6 3300 Sponta- neous vaginal Breech (un- diagnosed), fetal bradycardia, meconium 1, 3, 4 Yes 6.65 -20 No Yes 2 Abnormal: unilateral tha- lamic pattern of ischaemia/ infarction Ventilated Discharged home on day 7 of life Normal histology (external) 1, 2, 3, 4, HIE outborn 9 40+4 3030 Operative vaginal (ventouse) Fetal bradycar- dia, meconium stained liquor 0, 6, 7 No 6.8 -14.8 Yes Yes 2 Abnormal: tha- lamic pattern of ischaemia/ infarction Ventilated, multi-organ dysfunction Discharged home on day 8 of life No placenta in NMH 3, 4 HIE out- born 10 40+6 3720 Operative vaginal (ventouse) Reduced fetal movements, IOL, abnormal CTG 2, 4, 4 Yes 6.7 -18.2 Yes Yes 2 Abnormal: global pattern of ischaemia/ infarction Ventilated Transferred to referring hospital on day 8 of life Normal histology 1, 2, 3, 4 HIE outborn 11 41+0 3620 Emer- gency C-Section (GA) Reduced fetal movements, abnormal CTG 0, 1, 6 Yes 7.19 -7.6 No Yes 2 Normal Ventilated Discharged home on day 6 of life No placenta in NMH 2 HIE outborn 12 41+2 3705 Emer- gency C-Section (GA) Meconium stained liquor, abnormal CTG, failed instru- mental 0, 2, 4 Yes 6.83 -21.4 No Yes 3 Normal Ventilated Transferred to referring hospital on day 7 of life No placenta in NMH 1, 2, 3, 4 HIE outborn