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49 Neonatal Encephalopa y NMH Annual Rep t | 2020 Hypoxic Ischaemic Encephalopathy: Inborn (8) Case No. EGA BW (g) Delivery Method Delivery Method Indication Apgars 1, 5, 10, 15, 20 PPV at 10 mins Min pH within 60 min Max BE within 60 min Sei- zures Y/N TH Grade of NE Summary of MRI brain Organ Involve- ment Outcome Placental Histology Classi fication 1 36+5 2645 Emergency C-Section (not in labour) Reduced fetal movements and NRCTG 3,4,6 No 6.98 -12.1 Yes Yes 2 Abnormal - global pattern of ischaemia/ infarction Ventilated, Coagulopathy, Thrombocytope- nia, SIADH, AKI, Elevated LFTs Discharged home D8 High grade FVM. 3 2 37+6 2655 Emergency C-Section (not in labour) APH and fetal bra- dycardia 1,5,5,5 Yes 6.8 incalcu- lable Yes Yes 2 Abnormal - basal ganglia pattern of ischaemia/ infarction Ventilated, Inotropes, Thrombocytope- nia, SIADH, AKI, Elevated LFTs Discharged home D27 MVM with low grade FVM. 1,2,3,4 3 38+4 3005 Emergency C-Section (not in labour) Reduced fetal movements and NRCTG 0,4,6 Yes 7.03 -15.8 Yes Yes 3 Abnormal - global pattern of ischaemia/ infarction Ventilated, Ino- tropes, Hypergly- caemia, SIADH, AKI, Elevated LFTs Discharged home D10 High grade FVM and moderate MVM. 2 4 39+3 3275 Operative vaginal (Ventouse/ forceps) IOL for maternal PIH. Instrumental delivery for NRCTG. Meconium III at delivery 1,3,3,3 Yes 6.96 -14.1 Yes Yes 2 Normal Ventilated, Coag- ulopathy, SIADH, Elevated LFTs Discharged home D5 High grade FVM. 1,2,3 5 40+1 3480 Emergency C-Section (not in labour) Reduced fetal movements report- ed. Fetal bradycar- dia, abruption. 0,0,4,6,6 Yes 6.83 -19.4 Yes Yes 3 Not performed Ventilated, inhaled Nitric Oxide, Inotropes, Coagulopathy, Thrombocytope- nia, SIADH, AKI, Elevated LFTs Died D1. Delayed villous mat- uration with high grade FVM. 1,2,3,4 6 41+1 4295 Emergency C-Section (In labour) IOL for maternal PET/Hypertension. EmLSCS for IUA - inability to treat fetal intolerance (NRCTG and mater- nal pyrexia). Fetal bradycardia 3,4,6,6,9 No 6.73 -23.7 Yes Yes 3 Abnormal - global pattern of ischaemia/ infarction Ventilated, Ino- tropes, Throm- bocytopenia, Hyperglycaemia, Hypocalcaemia, SIADH, AKI, Ele- vated LFTs Patient Died (D7). Coro- ner's case No ab- normal histology. 3,4 7 41+2 3765 Operative vaginal (Ven- touse) IOL for post dates. Ventouse delivery for NRCTG 1,2,4 No 7.16 -6.6 No Yes 2 Normal Ventilated, SIADH Discharged home D6 DVM with low grade FVM. 1 8 41+5 4030 Spontaneous vaginal IOL for post dates. ROM x 22 hours. Maternal intrapar- tum pyrexia 3,4,5,7 Yes 6.92 -15.7 Yes Yes 3 Abnormal - basal ganglia pattern of ischaemia/ infarction Ventilated, SIADH Discharged home D12 Delayed villous maturation. Severe MIR and Severe FIR. 1,2,3