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134 Gynaecology and Colposcopy 2020 | NMH Annual Rep t infertility, not suitable for ICSI. This is a growing and successful service. (Tables 6+7) Child, Adolescent and Young Adult (CAYA) Fertility Preservation Services AYA Males: Eight adolescent males between the ages of 13 and 15 years were referred to MFC in 2020 for sperm cryopreservation services before undergoing gonadotoxic treatment or surgery. Their oncology diagnoses were: Ewings Sarcoma, T-cell Acute Lymphoblastic Leukaemia, Hodgkin's Lymphoma, Osteosarcoma, Acute Myeloid Leukaemia and Rhabdomyosarcoma. Of these 8 boys, 62.5% (n=5) produced a semen sample and 80% (n=4) had sperm of suitable quality for freezing. AYA Females: Four adolescent females (aged 14 to 16 years) were referred to MFC in 2020 for oocyte vitrification before undergoing gonadotoxic cancer therapy. Their oncology diagnoses were: Rhabdomyosarcoma, Medulloblastoma, Hodgkin's Lymphoma and Osteosarcoma. Three of these young women (75%) had a successful cycle, with a mean of 12 oocytes cryopreserved for future use. The 4 th young woman's attempt was cancelled due to her deteriorating medical condition. Six female survivors of CAYA cancer, who had previously received gonadotoxic treatment as part of their cancer therapy, attended MFC in 2020 for an initial fertility consultation. Research The Reproductive Medicine Department maintains an active and productive research portfolio, collaborating with scientists in Irish academic institutions such as UCD and TCD. MFC employs a full-time Research Officer and two Clinical Research Fellow posts exist for higher training in Reproductive Medicine & Surgery, with both fellows undertaking higher degrees. MFC also hosts PhD and MSc students. Research at MFC is aimed at improving knowledge, expertise and care pathways in the field of reproductive medicine. Our studies span a range of topics, from basic mechanistic biology to clinical translational research. In 2020, researchers at MFC also worked closely with collaborators at several of Ireland's leading academic research institutions, including University College Dublin and Trinity College Dublin, on the following research projects: • Innate immune factors, endometrial receptivity and infertility (Funding: Grant for Fertility Innovation, Merck) • Endometrial microbiome and infertility (Funding: Grant for Fertility Innovation, Merck) • Glycome analysis in endometriosis (NIBRT collaboration. Funding: Horizon 2020, Marie Curie International Fellowship) • Development of improved laboratory tests for sperm quality and function in male infertility (Funding: Irish Research Council) • Knowledge and attitudes towards fertility preservation among patients and healthcare providers • Ovarian Reserve in childhood cancer survivors Publications, Posters, Presentations and Invited Lectures are listed in the Appendices.