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52 Neonatal Encephalopa y 2020 | NMH Annual Rep t Seizures – No Encephalopathy: Inborn (4) Case No. EGA BW (g) Delivery Method Delivery Method Indication Apgars 1, 5, 10, 15, 20 PPV at 10 mins Min pH within 60 min Max BE within 60 min Sei- zures Y/N TH Grade of NE Summary of MRI brain Organ Involve- ment Outcome Histology Classification 1 35+6 3035 C-Sec- tion (Emer- gency) Em LSCS for breech, previ- ous LSCS and suspected arthrogryp- osis 6,9 No 7.35 -1.1 Yes (On D5) No 0 Extensive predom- inantly perisylvian polymicrogyria cortical malforma- tion as described which in the clinical context is sugges- tive of arthrogryp- osis multiplex con- genita. The brain biometry mea- surements are also outside 2 standard deviations below the mean. No Transferred to Crumlin D6 Gross only. Seizures secondary to underlying brain malfor- mation - No HIE/NE 2 38+5 3605 Emer- gency C-Sec- tion (In labour) LSCS for maternal medical reason/ pains and previous LSCS. 9,9 No 7.23 -3.2 Yes (sus- pected from around 6 hours of age) No 0 Agenesis of the corpus callosum. Temporoparietal pachygyria and malformation involving the basal ganglia and frontal horns of the lateral ventricles No Transferred to TSH D6. Died at < 1 year of life DVM and low grade FVM. Seizures secondary to genetic dis- order (XLAG = x-linked lissencephaly and abnormal genitalia) 3 39+1 4510 Oper- ative vaginal (Ven- touse) IOL for fetal macrosomia. Ventouse delivery for FTA. 9,9 No 7.26 -2 Yes (from 22 hours of age) No 0 Right sided haem- orrhagic stroke Nil Discharged Home D7 Low grade FVM. Seizures - No HIE/NE 4 41+5 3400 SVD IOL for PET/ hypertension and post- dates. 5,8 No 7.18 -7.3 Yes (from 7 hours of age) No 0 Punctate foci of ischaemia/ infarction in deep white matter of left frontal lobe and periventricular white matter of occipital lobes and splenium of corpus callosum Hypoglycae- mia, Hypona- traemia Discharged Home D7 Small placenta. Severe MIR and severe FIR. DVM. Seizures - No HIE/NE Classification: 1) Apgar score ≤5 at 10 mins of age 2) Continued need for resus at 10 mins after birth 3) pH <7.0 within 60 mins of birth 4) Base excess ≥ 16.0 within 60 mins of birth