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42 Neonatal and Infant M tality 2020 | NMH Annual Rep t Perinatal Mortality: Early Neonatal Deaths (12) Case No. EGA BW (g) Gender Delivery method Apgars (1, 5, 10 mins) Age at death (days) Place of death External Referral IUGR Placental Histology Cause of death PM 1 23+2 505 Female SVD 0, 4, 6 1 NICU Yes No Maternal and fetal inflammatory response, high grade FVM. Severe respiratory distress syndrome, suspected pulmonary hypoplasia, prolonged preterm rupture of membranes since at least 21 weeks, extreme prematurity secondary to ascending infection. No 2 23+2 615 Female SVD 0, 0, 1 1 NICU Yes No Placenta not sent. Severe respiratory distress syndrome, pulmonary hypoplasia, bilateral pneumothoraces, extreme prematurity. No 3 23+3 520 Female LSCS 5, 7 3 NICU No No DCDA. Hypoxic respiratory failure, refractory hypotension, extreme prematurity, extremely low birth weight, DCDA twin. No 4 24+2 490 Female LSCS 2, 8 7 NICU No Diagnosed at Delivery Severe MVM. Klebsiella sepsis, extreme prematurity, extremely low birth weight. No 5 25+0 945 Male LSCS 1, 1, 1 1 NICU No No Maternal and fetal inflammatory response. Severe acute chorioamnionitis. Severe pulmonary hypoplasia, prolonged preterm rupture of membranes since 21 weeks, extreme prematurity, extremely low birth weight, chorioamnionitis. Yes 6 25+4 575 Male LSCS 4, 8 7 NICU No Suspected antenatally Hypercoiled cord. E.Coli sepsis and multi-organ failure, extreme prematurity, extremely low birth weight. No 7 26+2 500 Female LSCS 7, 8 2 NICU Yes Suspected antenatally Severe MVM. Low grade villitis. Severe respiratory failure, respiratory distress syndrome, extreme prematurity secondary to PET, extremely low birth weight. No 8 27+2 1175 Female SVD 3,4,6 2 NICU Yes No Maternal and fetal inflammatory response. Severe acute chorioamnionitis. Pulmonary hypoplasia, prolonged preterm rupture of membranes from 19 weeks. Prematurity secondary to ascending infection. No 9 32+4 1880 Female LSCS 3, 5, 8 3 NICU No No Maternal and fetal inflammatory response. Severe acute chorioamnionitis. Pulmonary hypoplasia, prolonged preterm rupture of membranes from 18 weeks, prematurity secondary to PPROM. No 10 39+2 3380 Male SVD 9, 9 1 NICU No No High grade FVM. Group B strep sepsis. No 11 40+1 3480 Female LSCS 0, 0, 4 1 NICU No No Delayed villous maturation with high grade FVM. Neonatal encephalopathy, multi organ failure, placental abruption . No 12 41+1 4295 Female LSCS 3, 4, 6 7 NICU No No No abnormal histology. PM results awaited. Yes – Coroner's PM

